https://video.igem.org/videos/watch/032826a3-6c18-499c-9ffd-aa288a803b7d Title: INTESTINAL BARRIER Description: Our project designed and reported an engineered probiotic Escherichia coli Nissle 1917 (ECN1917) strain with a modified chassis genome. We integrated a dual-switch system into the engineered bacteria, which combines the AI-2 quorum sensing recognition system from intestinal Salmonella and the tetrathionate inflammation signal recognition system. This enables the early detection of disease signals within the gut microbiota, facilitates convenient diagnostics based on stool samples, and suppresses intestinal pathogens through the active expression of antimicrobial peptides. Wiki | Official Page Thu, 29 Oct 2026 22:24:34 GMT https://validator.w3.org/feed/docs/rss2.html PeerTube - https://video.igem.org https://video.igem.org/client/assets/images/icons/icon-1500x1500.png https://video.igem.org/videos/watch/032826a3-6c18-499c-9ffd-aa288a803b7d All rights reserved, unless otherwise specified in the terms specified at https://video.igem.org/about and potential licenses granted by each content's rightholder.