https://video.igem.org/videos/watch/081c9763-aa71-46a8-8dda-5afcda78f67a Title: Pioneering the next generation of RNAi‑based biopesticides Description: This video adopts scenario deduction to show our team’s discussion. Rapeseed is a globally vital oil‑crop, yet Sclerotinia sclerotiorum causes severe yield losses. Our strategy combines circular RNA and minicell technology to tackle this threat. Circular RNA closes free ends to resist enzymatic degradation. Minicell‑based production avoids the cell‑RNA separation step required in conventional in‑vivo synthesis. Moreover, minicells act as delivery carriers with an intelligent acid‑responsive release at infection sites for precise disease control. Bioinformatics software is used for custom circular RNA design, supporting the development of next‑generation green RNA pesticides. Wiki | Official Page Tue, 01 Sep 2026 16:54:34 GMT https://validator.w3.org/feed/docs/rss2.html PeerTube - https://video.igem.org https://video.igem.org/client/assets/images/icons/icon-1500x1500.png https://video.igem.org/videos/watch/081c9763-aa71-46a8-8dda-5afcda78f67a All rights reserved, unless otherwise specified in the terms specified at https://video.igem.org/about and potential licenses granted by each content's rightholder.