https://video.igem.org/videos/watch/1adc86f4-7afe-4a8a-a8ae-f6320148dbf3 Title: SweetCycle: Optimizing Steviol Glycoside Biosynthesis for Zero-Calorie Sweetener & Full Plant Circular Economy Description: Excessive added sugar brings severe public health burdens including obesity and type 2 diabetes. Stevia-derived Reb M and Reb D serve as perfect natural zero-calorie sweeteners, but their natural content is too limited for large-scale application. Team SweetCycle applies synthetic biology and enzyme engineering to redesign core enzymes UGT91D2 and UGT76G1 in stevia, significantly elevating the yield of high-quality Reb M and Reb D. We conduct preliminary verification with stevia hairy root cultures and propose a whole-stevia circular economy model: residual plant biomass after sweetener extraction is reused as functional animal feed to achieve zero waste. Ultimately, SweetCycle intends to deliver a sustainable, guilt-free sweet solution that balances human health and agricultural circular sustainability. Official Page Tue, 01 Sep 2026 16:54:35 GMT https://validator.w3.org/feed/docs/rss2.html PeerTube - https://video.igem.org https://video.igem.org/client/assets/images/icons/icon-1500x1500.png https://video.igem.org/videos/watch/1adc86f4-7afe-4a8a-a8ae-f6320148dbf3 All rights reserved, unless otherwise specified in the terms specified at https://video.igem.org/about and potential licenses granted by each content's rightholder.