https://video.igem.org/videos/watch/27efc2bf-6c52-4236-8a48-354667c21d23 This video shows a 100 ns molecular dynamics simulation of the Gpr2 N84V variant with ascr#18 in a membrane environment. Trajectory analysis identified persistent Arg189 anchoring of the ligand’s carboxylate group, accompanied by Lys364 contacts with its sugar group. These interactions provide a structural explanation for how the ligand maintains this binding pose. The receptor is shown in pale purple and ascr#18 in coral pink. Simulation and visualization: NKU-China 2026 team. Wiki: https://2026.igem.wiki/nku-china/model-md/ Wed, 21 Oct 2026 02:54:10 GMT https://validator.w3.org/feed/docs/rss2.html PeerTube - https://video.igem.org https://video.igem.org/client/assets/images/icons/icon-1500x1500.png https://video.igem.org/videos/watch/27efc2bf-6c52-4236-8a48-354667c21d23 All rights reserved, unless otherwise specified in the terms specified at https://video.igem.org/about and potential licenses granted by each content's rightholder.