https://video.igem.org/videos/watch/3300da9d-2227-45dc-aead-985601b39553 Title: NucleArk | A Tiny Vessel Through the Nuclear Barrier Description: Efficient nuclear delivery into slowly dividing cells remains a major challenge, particularly for large nucleic acids such as plasmids. Yet, many such cells—including retinal cells, cardiomyocytes, and neurons—are critical therapeutic targets in the human body. This delivery bottleneck has significantly hindered genetic therapies targeting these cell types. By leveraging the high biocompatibility, low biotoxicity, and efficient cargo encapsulation capacity of phase-separated droplets, we aim to establish a safe and effective platform for plasmid nuclear delivery.This video underlines all major components discussed and highlights main findings. To find out more about NucleArk, visit our Wiki! Wiki | Official Page Thu, 29 Oct 2026 22:26:47 GMT https://validator.w3.org/feed/docs/rss2.html PeerTube - https://video.igem.org https://video.igem.org/client/assets/images/icons/icon-1500x1500.png https://video.igem.org/videos/watch/3300da9d-2227-45dc-aead-985601b39553 All rights reserved, unless otherwise specified in the terms specified at https://video.igem.org/about and potential licenses granted by each content's rightholder.