https://video.igem.org/videos/watch/4194f735-46e4-4d82-9005-c542671aa853 Lesson 4 explores why DDI prediction becomes harder for emerging drugs. It introduces old–old, old–new, and new–new settings, explains why random splits can overestimate performance, and shows how distribution shift and DDI-Ben provide a more realistic way to evaluate new-drug generalization. https://2026.igem.wiki/edgesci-thu-china Tue, 20 Oct 2026 02:55:42 GMT https://validator.w3.org/feed/docs/rss2.html PeerTube - https://video.igem.org https://video.igem.org/client/assets/images/icons/icon-1500x1500.png https://video.igem.org/videos/watch/4194f735-46e4-4d82-9005-c542671aa853 All rights reserved, unless otherwise specified in the terms specified at https://video.igem.org/about and potential licenses granted by each content's rightholder.