https://video.igem.org/videos/watch/478afb2a-22f7-4d4a-93f6-891ac2ae4733 Title: FLAME: Functional Layered Anti-tumor Microbial Executor Description: FLAME explores an engineered Escherichia coli Nissle 1917 (EcN) platform for colorectal cancer research, combining environmentally responsive expression with GSDMD-N, the pore-forming fragment of gasdermin D. Our central challenge is balancing bacterial survival with effector activity. In this presentation, Suda-ICPI-China shares our chassis selection, circuit construction and testing, effector comparisons, and modeling insights into promoter choice and delivery limits. We also explain how Human Practices and Education shaped our evaluation and communication of the project. Wiki | Official Page Thu, 29 Oct 2026 22:23:43 GMT https://validator.w3.org/feed/docs/rss2.html PeerTube - https://video.igem.org https://video.igem.org/client/assets/images/icons/icon-1500x1500.png https://video.igem.org/videos/watch/478afb2a-22f7-4d4a-93f6-891ac2ae4733 All rights reserved, unless otherwise specified in the terms specified at https://video.igem.org/about and potential licenses granted by each content's rightholder.