https://video.igem.org/videos/watch/50a7d7ba-f3ca-45f1-9c74-db09e1d093cb Most commercial gene synthesis providers will not produce highly repetitive sequences under standard pricing. Repetitive genes fail the sequence-complexity filters that vendors run before a synthesis order is accepted, so the order is either rejected outright or pushed into a bespoke, high-cost, long-lead-time service. This is not an arbitrary policy. The repetitive sequences create problems with synthesis as the DNA complex and mis- or self-anneal. For iGEM teams working with repetitive sequences like Elastin-like polypeptides, synthesis is a critical bottleneck. This creates a significant disadvantage since major iGEM sponsors like IDT and GenScript restrict synthesis of repetitive DNA. We have designed, built and validated a browser-based designer "MOSAIC Designer" that generates synthesis-ready library sequences, and that ships with our tested MOSAIC library genes. Check it out on our wiki Made by our wiki manager Bora with the help of our Dry Lab manager: Zhenya Tue, 20 Oct 2026 02:54:40 GMT https://validator.w3.org/feed/docs/rss2.html PeerTube - https://video.igem.org https://video.igem.org/client/assets/images/icons/icon-1500x1500.png https://video.igem.org/videos/watch/50a7d7ba-f3ca-45f1-9c74-db09e1d093cb All rights reserved, unless otherwise specified in the terms specified at https://video.igem.org/about and potential licenses granted by each content's rightholder. https://video.igem.org/w/aXErjM7qVeTq4uhKxfBkP2;threadId=139 https://video.igem.org/w/aXErjM7qVeTq4uhKxfBkP2;threadId=139 Mon, 19 Oct 2026 22:10:03 GMT Great video 😃

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