https://video.igem.org/videos/watch/53b762f2-b639-48f8-956a-640780390053 Title: CHIRALYS: Through the mirror, the future of aptamers Description: Our team iGEM Toulouse has designed next-generation DNA aptamers to bind proteins, pathogens or cancer cells with unprecedented stability. Current aptamers built from “right-handed” nucleotides, the natural chirality found in biology, are prone to degradation in the human body and in a physiological environment. We propose to create mirror-image, “left-handed” aptamers that will evade natural degradation mechanisms, enhancing their long-term binding capabilities. We devised experimental and in silico strategies to design, produce, and characterize mirror aptamers targeting peptides and proteins. Moreover, we engaged in the debate about the risks and ethical issues of creating a “mirror life”. Wiki | Official Page Tue, 01 Sep 2026 16:55:42 GMT https://validator.w3.org/feed/docs/rss2.html PeerTube - https://video.igem.org https://video.igem.org/client/assets/images/icons/icon-1500x1500.png https://video.igem.org/videos/watch/53b762f2-b639-48f8-956a-640780390053 All rights reserved, unless otherwise specified in the terms specified at https://video.igem.org/about and potential licenses granted by each content's rightholder.