https://video.igem.org/videos/watch/68ee58e9-1b78-40a2-a254-9199796265f0 Title: Secure the Future, Capture the Cure Description: In an ICU, a culture takes 48 to 72 hours, and a full report four to seven days. Treatment starts on a guess, and every wrong guess selects for resistance. Project Capture turns one molecule into two tools. Pseudomonas aeruginosa coordinates its virulence with 3-oxo-C12-HSL. System 1 gives E. coli the pathogen’s own LasR receptor, so the signal switches on sfGFP. System 2 uses an engineered retron to make the Cb-2 aptamer inside the cell, binding the signal so the message never arrives. Our retron-Cb-2 extract reduced swarming motility by 19%, pyocyanin by 26% and biofilm formation by 34%. We also built CAPTURE-Screen, a bench-top fluorescence reader costing US$54 to US$161 instead of thousands, in two versions anyone can copy; LasReader, a browser-based analysis platform; and three models. Alongside the lab work, we ran a nationwide survey, interviewed clinicians, held 17 outreach events across Taiwan, and worked with 11 iGEM teams. NCKU-Tainan, iGEM 2026 Wiki: https://2026.igem.wiki/ncku-tainan/ AI use: Claude (Anthropic) was used to produce the schematic animations in this video. All other content is the team’s own work. Wiki | Official Page Thu, 29 Oct 2026 22:25:53 GMT https://validator.w3.org/feed/docs/rss2.html PeerTube - https://video.igem.org https://video.igem.org/client/assets/images/icons/icon-1500x1500.png https://video.igem.org/videos/watch/68ee58e9-1b78-40a2-a254-9199796265f0 All rights reserved, unless otherwise specified in the terms specified at https://video.igem.org/about and potential licenses granted by each content's rightholder.