https://video.igem.org/videos/watch/71f9f5be-f476-49f5-af17-2a9f392193a6 Title: Chariot: A Platform Technology for OMV-based Therapeutics Description: Bacterial outer membrane vesicles (OMVs) are promising drug delivery vector and vaccine platforms, but their biomanufacturing is limited by low yields, high variability, and costly manufacturing. We present Chariot, an end-to-end platform for the design of vesicle nucleating peptide (VNp)-tagged therapeutics for high-yield OMV loading. We validate the use of VNp for loading various types of molecular cargo into OMVs, and highlight its benefits for combatting antimicrobial-resistant infections. Overall, Chariot enables robust OMV bioengineering for innovative, targeted therapeutic development. Wiki | Official Page Tue, 01 Sep 2026 16:55:41 GMT https://validator.w3.org/feed/docs/rss2.html PeerTube - https://video.igem.org https://video.igem.org/client/assets/images/icons/icon-1500x1500.png https://video.igem.org/videos/watch/71f9f5be-f476-49f5-af17-2a9f392193a6 All rights reserved, unless otherwise specified in the terms specified at https://video.igem.org/about and potential licenses granted by each content's rightholder.