https://video.igem.org/videos/watch/72d5264c-8462-471c-acc6-5fa325e2542d Title: C.L.E.A.R. - Cutibacterium acne Living Engineering for Acne & Homeostasis Regulation Description: Acne has never been just about the skin. The looking away, the sighs in front of the mirror, the instinct to turn your face aside — we know this sense of inferiority all too well. That's why we, AIS‑China, decided to take a different approach. Instead of trying to eliminate the bacteria on the skin, we repurposed non-pathogenic Cutibacterium acnes as a living therapeutic platform. Our engineered C.L.E.A.R. strain improves colonization fitness to outcompete acne-causing strains in the follicle, and releases anti-inflammatory SOD upon sensing excess fatty acids — a key trigger in the acne microenvironment. Once its task is complete, it safely self-destructs via a controlled triple-layer kill-switch system. That's how we C.L.E.A.R. acne and restore self-confidence. Engineered Balance, Healthier Skin Wiki | Official Page Sat, 29 Aug 2026 17:17:30 GMT https://validator.w3.org/feed/docs/rss2.html PeerTube - https://video.igem.org https://video.igem.org/client/assets/images/icons/icon-1500x1500.png https://video.igem.org/videos/watch/72d5264c-8462-471c-acc6-5fa325e2542d All rights reserved, unless otherwise specified in the terms specified at https://video.igem.org/about and potential licenses granted by each content's rightholder.