https://video.igem.org/videos/watch/780f6abc-4e3e-4dc9-b9ce-6f3cc32c3e4b Title: HIV lingers in remote locations in the body. We're conducting a heist to find and disable the virus. Description: Antiretroviral therapy suppresses HIV but cannot clear the integrated provirus. SprayAway delivers CRISPR a compact eukaryotic RNA-guided nuclease, in engineered extracellular vesicles to excise proviral DNA at conserved LTR sites. Entropy-guided guide selection across LANL sequence data yields Tier 1 candidates validated in Jurkat latency models. Transient, low-immunogenicity delivery permits iterative redosing, progressively depleting the latent reservoir toward functional cure. Official Page Tue, 01 Sep 2026 16:53:17 GMT https://validator.w3.org/feed/docs/rss2.html PeerTube - https://video.igem.org https://video.igem.org/client/assets/images/icons/icon-1500x1500.png https://video.igem.org/videos/watch/780f6abc-4e3e-4dc9-b9ce-6f3cc32c3e4b All rights reserved, unless otherwise specified in the terms specified at https://video.igem.org/about and potential licenses granted by each content's rightholder.