https://video.igem.org/videos/watch/9c1dfdf6-9175-4169-beea-852ea3a9e635 Title: Engineering biology for a healthier smile-A potential daily oral-care solution Description: Dental plaque and calculus are major contributors to oral diseases such as cavities, gingivitis, and periodontitis. Current removal methods rely on mechanical brushing or harsh chemicals, which are often incomplete or inconvenient. Our project engineers a synergistic biological solution combining three enzymes—DNase, protease, and glycosidase—to break down the key components of biofilm matrix (DNA, proteins, and polysaccharides), thereby dispersing existing plaque and preventing new buildup. Additionally, we design antimicrobial peptides that bind directly to tooth surfaces, inhibiting bacterial reattachment and growth. Together, this system offers a targeted, non-toxic, and easy-to-use approach to reduce plaque accumulation and inhibit calculus formation, promoting long-term oral health. Wiki | Official Page Thu, 29 Oct 2026 22:21:32 GMT https://validator.w3.org/feed/docs/rss2.html PeerTube - https://video.igem.org https://video.igem.org/client/assets/images/icons/icon-1500x1500.png https://video.igem.org/videos/watch/9c1dfdf6-9175-4169-beea-852ea3a9e635 All rights reserved, unless otherwise specified in the terms specified at https://video.igem.org/about and potential licenses granted by each content's rightholder.