https://video.igem.org/videos/watch/9dedd3e6-ed96-4c33-8ecc-41fe6e7ccba0 Title: Too hungry to eat Description: The video explores why satiation, the feeling of fullness, creates a major barrier in treating malnutrition. It explains that many undernourished children and older adults struggle not because food isn’t available, but because their bodies signal “I’m full” too quickly, limiting nutrient intake. To address this, the video introduces a fascinating approach: using a fatty acid amide hydrolase (FAAH) enzyme produced by a specific gut microbe to “trick” the body’s satiation system. The research team has engineered a probiotic bacterium that expresses FAAH, allowing it to break down the molecular signals that trigger the sensation of fullness. By reducing premature satiation, this strategy could help children with malnutrition consume more nutrients and could also support older adults experiencing anorexia or loss of appetite, ultimately promoting healthier intake and better recovery. Wiki | Official Page Tue, 01 Sep 2026 16:53:20 GMT https://validator.w3.org/feed/docs/rss2.html PeerTube - https://video.igem.org https://video.igem.org/client/assets/images/icons/icon-1500x1500.png https://video.igem.org/videos/watch/9dedd3e6-ed96-4c33-8ecc-41fe6e7ccba0 All rights reserved, unless otherwise specified in the terms specified at https://video.igem.org/about and potential licenses granted by each content's rightholder.