https://video.igem.org/videos/watch/a5c3d5f2-74df-4cea-b3ce-1b60696787c7 Title: SENTINEL Description: SENTINEL, short for Sparse autoencoder Engineering of Novel Target-binding proteins for Interpretable Neurobiomarker Evaluation and Localized detection, is a project about engineered protein biosensors. These sensors hold transformative potential for real-time disease detection, yet their development remains largely empirical. Current generative protein design models function as unexplained systems — candidates emerge without visible reasoning for why some bind strongly while others fail. Project Sentinel introduces an interpretable framework for creating novel protein binders by applying sparse autoencoders to ESM-C representations of generated designs. Wiki | Official Page Thu, 29 Oct 2026 21:22:06 GMT https://validator.w3.org/feed/docs/rss2.html PeerTube - https://video.igem.org https://video.igem.org/client/assets/images/icons/icon-1500x1500.png https://video.igem.org/videos/watch/a5c3d5f2-74df-4cea-b3ce-1b60696787c7 All rights reserved, unless otherwise specified in the terms specified at https://video.igem.org/about and potential licenses granted by each content's rightholder.