https://video.igem.org/videos/watch/b6e63139-78d6-4d35-b322-045d1150a341 Title: ChemoGuard: A Toolkit for Pre-Treatment DPYD Genotyping to Prevent Severe Fluoropyrimidine Toxicity Description: This video presents ChemoGuard, a modular qPCR system designed to detect seven DPYD Tier 1 variants associated with severe 5-FU chemotherapy toxicity. We explain the scientific rationale, assay design, engineering cycle, and experimental validation, including the detection of all 66 expected probe signals with no signal in no-template controls. We also present our human practices, including stakeholder interviews, public engagement, and efforts to understand the need for accessible pharmacogenetic testing in Kazakhstan. Wiki | Official Page Thu, 29 Oct 2026 22:25:52 GMT https://validator.w3.org/feed/docs/rss2.html PeerTube - https://video.igem.org https://video.igem.org/client/assets/images/icons/icon-1500x1500.png https://video.igem.org/videos/watch/b6e63139-78d6-4d35-b322-045d1150a341 All rights reserved, unless otherwise specified in the terms specified at https://video.igem.org/about and potential licenses granted by each content's rightholder.