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        <title>UNC-Chapel Hill: How We're Rewiring the Gut to Prevent Colorectal Cancer Early (2026) - Project Promotion</title>
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        <description>Title: How We're Rewiring the Gut to Prevent Colorectal Cancer Early Description: Colorectal cancer remains both one of the most diagnosed and one of the most deadly cancers worldwide, with rising rates impacting younger populations and stumping doctors, all while patient screenings usually catch the disease too late. In this video, you can meet the UNC iGEM team and our project, CRYPTIC: a probiotic pill designed to target colorectal cancer before a tumor forms. By engineering E. coli Nissl to shift tryptophan metabolism away from the harmful kynurenine pathway and toward protective indole metabolites, CRYPTIC aims to overall restore gut balance and prevent the development of colorectal cancer. 2026 University of North Carolina at Chapel Hill (UNC) iGEM #iGEM #SyntheticBiology #ColorectalCancer #SyntheticBiology #Oncology Village Official Page</description>
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