Main knilpot channel https://video.igem.org/c/knilpot_channel/videos Mon, 19 Oct 2026 02:55:27 GMT https://validator.w3.org/feed/docs/rss2.html PeerTube - https://video.igem.org Main knilpot channel https://video.igem.org/client/assets/images/icons/icon-1500x1500.png https://video.igem.org/c/knilpot_channel/videos All rights reserved, unless otherwise specified in the terms specified at https://video.igem.org/about and potential licenses granted by each content's rightholder. https://video.igem.org/feeds/podcast/videos.xml?videoChannelId=3884 <![CDATA[Munich: Primetheus (2026) [English]]]> https://video.igem.org/w/cRh8rjbSbctB4DfTbqdLEQ https://video.igem.org/w/cRh8rjbSbctB4DfTbqdLEQ Sun, 18 Oct 2026 18:43:35 GMT While nuclear genome engineering has advanced rapidly, mitochondrial gene editing remains fundamentally unexplored, current methods being limited to specific single nucleotide substitutions. Prime editing is a gene editing system consisting of a Cas nickase fused to a reverse transcriptase (RT) and a prime editing guide RNA (pegRNA) used as a template to synthesize a new, edited strand without introducing double-strand DNA breaks. Our project Primetheus adapts this system for mitochondria through separate import of the fused Cas-RT complex and the pegRNA into mitochondria. To overcome the technical challenge of verifying intra-mitochondrial RNA delivery, we are also developing a novel, genetically encoded RNA-based readout system to enable continuous live-cell RNA monitoring. Primetheus will enable researchers to introduce a wider range of edits, including all base substitutions, as well as longer insertions into mitochondrial DNA, allowing in-depth studies of the mitochondrial genome and unlocking new therapeutic approaches.

https://2026.igem.wiki/munich

]]> Main knilpot channel Science & Technology nonadult Munich: Primetheus (2026) [English] While nuclear genome engineering has advanced rapidly, mitochondrial gene editing remains fundamentally unexplored, current methods being limited to specific single nucleotide substitutions. Prime editing is a gene editing system consisting of a C... <![CDATA[Munich: Wet Lab Intro for Dummies (2026) [German]]]> https://video.igem.org/w/oBedZSpykzg3Fktd7Yt8Yo https://video.igem.org/w/oBedZSpykzg3Fktd7Yt8Yo Sun, 18 Oct 2026 17:17:15 GMT Our wet lab team gives a brief tour and summary about wet-lab work. Produced for the Zamanand Festival 2026.

https://2026.igem.wiki/munich

]]> Main knilpot channel Science & Technology nonadult Munich: Wet Lab Intro for Dummies (2026) [German] Our wet lab team gives a brief tour and summary about wet-lab work. Produced for the Zamanand Festival 2026. https://2026.igem.wiki/munich <![CDATA[Munich: Interview with Invitris Co-Founder Kilian Vogele (2026) [English]]]> https://video.igem.org/w/foJYvFJvjBahV5PfL2hCxf https://video.igem.org/w/foJYvFJvjBahV5PfL2hCxf Sun, 18 Oct 2026 15:06:57 GMT A summary of our interview with previous iGEM participant and Co-founder of Invitris Kilian Vogele. Produced for the Zamanand Festival 2026.

https://2026.igem.wiki/munich

]]> Main knilpot channel Science & Technology nonadult Munich: Interview with Invitris Co-Founder Kilian Vogele (2026) [English] A summary of our interview with previous iGEM participant and Co-founder of Invitris Kilian Vogele. Produced for the Zamanand Festival 2026. https://2026.igem.wiki/munich <![CDATA[Munich: Synthetic Biology for Dummies at Zamanand Festival (2026) [German]]]> https://video.igem.org/w/grtCzBVXVzEpPehQhiBG6s https://video.igem.org/w/grtCzBVXVzEpPehQhiBG6s Sun, 18 Oct 2026 14:55:50 GMT On our mission to explain the mysterious term of synthetic biology, we show visitors of the Zamanand Festival in Munich 2026 what engineering strategies are used, what the central biological dogma is and how we use gene editing for our project Primethius, using simple drawings and analogies.

https://2026.igem.wiki/munich

]]> Main knilpot channel Science & Technology nonadult Munich: Synthetic Biology for Dummies at Zamanand Festival (2026) [German] On our mission to explain the mysterious term of synthetic biology, we show visitors of the Zamanand Festival in Munich 2026 what engineering strategies are used, what the central biological dogma is and how we use gene editing for our project Pri... <![CDATA[Munich: Street Interviews - What is Synthetic Biology? (2026) [German]]]> https://video.igem.org/w/x9KL4u2htGsV2v9vVupiYH https://video.igem.org/w/x9KL4u2htGsV2v9vVupiYH Sun, 18 Oct 2026 12:48:24 GMT In early June 2026, we asked nearly 40 people from Munich, Freising, and Garching what they knew about synthetic biology, and inquired their thoughts and opinions on potential applications

https://2026.igem.wiki/munich

]]> Main knilpot channel Science & Technology nonadult Munich: Street Interviews - What is Synthetic Biology? (2026) [German] In early June 2026, we asked nearly 40 people from Munich, Freising, and Garching what they knew about synthetic biology, and inquired their thoughts and opinions on potential applications https://2026.igem.wiki/munich